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KMID : 0360919650080100955
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Journal of the Korean Medical Association
1965 Volume.8 No. 10 p.955 ~ p.961
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OXYGEN CONSUMPTION AND CARDIAC OUTPUT IN THE HYPOTHERMIC DOG
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姜振聲/Kang, Jin Sung
李聖行/Lee, Sung Haing
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Abstract
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A study was carried out to determine oxygen consurption, cardiac output and other factors occurring in 15 hypothermic dogs. Hypothermia, rang-ing from normal to 17℃ of esophageal temperature was achieved by means of body surface cooling with ice water.
Results were as follows;
1) The O₂content of arterial blood did not change significantly during hypothermia. Both the O₂content of venous blood and the a-V O₂difference decreased progressively during the cooling period from 38℃ to 25℃. Below 25℃ a gradual increase was observed.
2) The CO₂content of arterial blood was not markedly altered during cooling except for falling at 17℃
However, the CO₂ content of venous blood decreased progressively during hypothermia. The pattern of V-a CO₂ difference was similiar to a-V O₂difference.
3) The CO₂ consumption of those dogs subjected to immersion hypothermia was markedly diminished .At 22℃, a value of 27.9% of the normal was observed.
4) Cardiac output at this same low temperature was reduced to 22% of the normal. No stroke volume change was noted.
5) At 22℃, the CI and the LVW also were reduced to 22% and 8% respectively of the normal.
6) Pulse rate and blood pressure diminished ashypothermia progressed. Pulse rate decreased from anormal mean value of 150 per minute to 40 perminute at 22℃. Blood pressure fell from a normalvaiue of 114 mm.Hg to 44 mm.Hg at esophageal temperature of 22℃
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